Operational business is conducted from Germany, while the medical study staff is active in the study centers on site and/or at the study participants’ homes. In addition, we work with local project managers in the respective target country who can take over personnel management and train the study staff. It is a matter of course for us that they speak the respective national language at least fluently. In order to be as close to the project and responsive as possible despite the distance, we regularly exchange information with the project managers and other stakeholders, for example in weekly meetings. We also attend important meetings on site. The results from the discussions are incorporated into our reporting to you.